Philadelphia Chromosome

An aberrant form of human CHROMOSOME 22 characterized by translocation of the distal end of chromosome 9 from 9q34, to the long arm of chromosome 22 at 22q11. It is present in the bone marrow cells of 80 to 90 per cent of patients with chronic myelocytic leukemia (LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE).

Also Known As:

Ph 1 Chromosome; 1 Chromosomes, Ph; Chromosome, Ph 1; Chromosome, Ph1; Chromosome, Philadelphia; Chromosomes, Ph 1; Chromosomes, Ph1; Ph 1 Chromosomes; Ph1 Chromosomes; Ph1 Chromosome

Cells
- Cellular Structures
  - Chromosomes
    - Mammalian Chromosomes
      - Human Chromosomes
        21-22 and Y Human Chromosomes
        Pair 22 Human Chromosomes
        Philadelphia Chromosome: 2714
        6-12 and X Human Chromosomes
        Pair 9 Human Chromosomes
        Philadelphia Chromosome: 2714
Signs and Symptoms Pathological Conditions
- Pathologic Processes: 10385
  - Chromosome Aberrations: 11465
    - Genetic Translocation: 2748
      - Philadelphia Chromosome: 2714
Genetic Phenomena
- Genetic Structures
  - Chromosomes
    - Mammalian Chromosomes
      - Human Chromosomes
        21-22 and Y Human Chromosomes
        Pair 22 Human Chromosomes
        Philadelphia Chromosome: 2714
        6-12 and X Human Chromosomes
        Pair 9 Human Chromosomes
        Philadelphia Chromosome: 2714
- Genetic Variation
  - Mutation
    - Chromosome Aberrations: 11465
      - Genetic Translocation: 2748
        Philadelphia Chromosome: 2714

A Zeifman Selected Research

A Zeifman Research Topics

Disease

Drug/Important Bio-Agent (IBA)